This study investigates the cognitive function and psychiatric status of patients undergoing surgery before and after exposure to Combined Inhalation Intravenous Anaesthesia (CIIA) and Total Intravenous Anaesthesia (TIVA) in tertiary institutions in Ekiti State. The research aims to assess immediate post-operative changes in cognitive function and psychiatric status among surgical patients receiving different anaesthesia methods. Using a quantitative descriptive research design, data was collected from a sample of 148 surgical patients across three tertiary hospitals in Ekiti State. The Mini-Mental State Examination (MMSE), Generalized Anxiety Disorder 7 (GAD-7), and Patient Health Questionnaire 9 (PHQ-9) were utilized to evaluate cognitive function and psychiatric status before and after anaesthesia. Findings indicate that while some minor variations were observed in cognitive and psychiatric measures post-anaesthesia, the majority of patients exhibited stable mental health indicators. Statistical analyses revealed no significant associations between socio-demographic variables (age, ethnicity, education) and cognitive or psychiatric outcomes post-anaesthesia. This study contributes to understanding the immediate impacts of anaesthesia on cognitive and psychiatric states in surgical patients, emphasizing the need for tailored perioperative care strategies. Healthcare providers should prioritize comprehensive patient education and routine mental health screening to manage expectations and mitigate potential postoperative complications.

Keywords: Cognition Function, Psychiatric Status, Patients, Surgery, General Anaesthesia,