LBP is one of the major musculoskeletal disorders which affect the nerves, tendons, ligaments, and all its associates’ structures. So many scholars have carried out studies on the Low Back Pain among Nurses but only a limited number of studies could be found that evaluated the knowledge of nurses about the prevention and self-treatment principles for LBP. This study accessed the outcome of a nurse-led intervention on knowledge of prevention of LBP among the participants. The study utilizes one group pre-test post-test quasi-experimental research to assess the effect of an educational intervention on knowledge of prevention of LBP among nurses. The total Population of the nurses is 258. Simple random technique was used to select the participants for this study. The sample size of 160 was determined using Leslie Kish’s formula.  A test paper was used for data collection. The questionnaire was made up of two sections. Section A contains 5 items that measured the participants’ socio-demographic ratings while section B assessed the knowledge of prevention of LBP. Reliability of the instrument was determined using Cronbach’s alpha model technique to ensure internal consistency of the instrument. Thus, Cronbach’s alpha value was 0.871. Data collection was in three phases while the data collected were subjected to descriptive and inferential statistics. The findings of the study revealed that the intervention programme improved the knowledge of nurses on the prevention of LBP among nurses. The improvement in the knowledge mean score of participants on prevention of LBP did not occur by chance but due to educational intervention been exposed to. It was recommended among others that there should be establishment of in-service educational program to provide continuous education for nurses aiming to refresh their knowledge on the prevention of LBP

Keywords: Low Back Pain, Outcome, Nursing Intervention, Prevention,

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