The rising incidence of diabetes mellitus worldwide and its possible impact on the health-related quality of life of the individuals affected constitute a serious cause for concern. Type-2 Diabetes Mellitus (T2DM) has been described as a chronic metabolic disease with an increasing prevalence worldwide, which is contributing to increasing cases of morbidity, mortality and negatively impacts on the health-related quality of life of the sufferers. The clinical predictors include the presence of co-morbidities, duration of illness, Body Mass Index (BMI) and glycosylated haemoglobin (HBA1c). The study utilized the descriptive survey design. Total enumeration was used to recruit 200 patients with T2DM. Research instrument consist of a self-developed questionnaire incorporating the WHOQOL-BREF. Descriptive and inferential statistics were used to analyze the collected data. Findings revealed that 108 (54%) of the participants were males while 92 (46%) were females. The health-related quality of life of the participants revealed 22% relatively high, 64.5% moderate, and 13.5% low. Comorbidity (ß=0.144, t=2.046, p<0.005), Presence of foot ulcer (ß=0.155, t=2.419, p<0.005) and hemoglobin A 1c (HbA1c) (ß=0.178, t=2.563, p<0.005) significantly predicted the health-related quality of life among patients with T2DM, while BMI (ß=0.023, t=0.323, p>0.005) did not show any significant prediction. In conclusion the study revealed the health-related quality of life of the majority of the patients with T2DM as moderate, although most of the participants rated their quality of life as good many were not satisfied with their health. It is therefore recommended that there is a need for patients with type-2 diabetes mellitus, nurses, and health-care providers to intensify efforts in the education, care management and prevention of complications in other to sustain and improve the health-related quality of life of patients.

Keywords: Diabetes Mellitus, Health-related Quality of Life, Clinical Predictors,

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